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IgM is a highly conserved antibody in vertebrates and is expressed early during immune response. It exists as a pentamer and is secreted by peritoneal B cells.
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Innovative Grade US Origin Chicken Serum 50ml - Innovative Grade US Origin Chicken Serum from Innovative Research is manufactured using whole blood collections from chickens in USDA-approved facilities. The animals used for this material are of US Origin, ensuring that only the highest-quality material is used for the production of the serum.
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Innovative Grade US Origin Guinea Pig Serum 10ml - Innovative Grade US Origin Guinea Pig Serum from Innovative Research is manufactured using whole blood collections from guinea pigs. The animals used for this material are of US Origin, ensuring that only the highest-quality material is used for the production of the serum.
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Innovative Grade US Origin Guinea Pig Complement Serum 10ml - Innovative Grade US Origin Guinea Pig Complement Serum from Innovative Research is manufactured using whole blood collections from guinea pigs. The animals used for this material are of US Origin, ensuring that only the highest-quality material is used for the production of the serum. This product is processed using a proprietary process that preserves complement activity. We do not recommend thawing this product for aliquoting, as this can impact the complement activity
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Innovative Grade US Origin Hamster Syrian Gold Serum 10ml - Innovative Grade US Origin Hamster Syrian Gold Serum from Innovative Research is manufactured using whole blood collections from type Syrian Gold hamsters. The animals used for this material are of US Origin, ensuring that only the highest-quality material is used for the production of the serum.
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Innovative Grade US Origin Bovine Serum 500ml - Innovative Grade US Origin Bovine Serum from Innovative Research is manufactured using whole blood collections from cows in USDA-approved facilities. The animals used for this material are of US Origin, ensuring that only the highest-quality material is used for the production of the serum.
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Innovative Grade US Origin Bovine Serum 100ml - Innovative Grade US Origin Bovine Serum from Innovative Research is manufactured using whole blood collections from cows in USDA-approved facilities. The animals used for this material are of US Origin, ensuring that only the highest-quality material is used for the production of the serum.
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TGF- 1 (transforming growth factor beta 1) is one of three closely related mammalian members of the large TGF- 1 superfamily that share a characteristic cystine knot structure TGF- 1 -2 and -3 are highly pleiotropic cytokines that act as cellular switches to regulate processes such as immune function proliferation and epithelial-mesenchymal transition Each TGF- isoform has some non-redundant function for TGF- 1 mice with targeted deletion show defects in hematopoiesis and endothelial differentiation and died of overwhelming inflammation TGF- 1 signaling begins with high-affinity binding to a type II ser/thr kinase receptor termed TGF- RII This receptor then phosphorylates and activates a second ser/thr kinase receptor TGF- RI (also called activin receptor like kinase (ALK)-5) or alternatively ALK-1 This complex phosphorylates and activates Smad proteins that regulate transcription
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